The HICCC Cytogenetics Shared Resource provides both classical cytogenetic services (i.e. karyotyping, FISH, SKY) as well as state of the art modern DNA damage and DNA repair assays (i.e. kinetic analyses of DNA damage induced foci, comet assay, sister-chromatid exchange, etc.) . There are two special functional microscopes and multifunctional analytic software in place. The Carl Zeiss Axio Imager Z2 microscope is equipped with Metafer software including MSearch, MetaCyte and AutoCapt modules and can perform automatic scanning,capture of metaphase/fluorescence imaging. The GenASIs platform installed in the Nikon Eclipse E800 microscope supports G/R/C/Q-banding, FISH, and SKY.